diff --git a/crypto/fipsmodule/rand/getrandom_fillin.h b/crypto/fipsmodule/rand/getrandom_fillin.h
index c0dea35..0f290e9 100644
--- a/crypto/fipsmodule/rand/getrandom_fillin.h
+++ b/crypto/fipsmodule/rand/getrandom_fillin.h
@@ -30,8 +30,6 @@
 #define EXPECTED_NR_getrandom 278
 #elif defined(OPENSSL_ARM)
 #define EXPECTED_NR_getrandom 384
-#elif defined(OPENSSL_PPC64LE)
-#define EXPECTED_NR_getrandom 359
 #elif defined(OPENSSL_RISCV64)
 #define EXPECTED_NR_getrandom 278
 #endif
diff --git a/include/openssl/base.h b/include/openssl/base.h
index 690b801..190e250 100644
--- a/include/openssl/base.h
+++ b/include/openssl/base.h
@@ -96,9 +96,6 @@
 #elif defined(__ARMEL__) || defined(_M_ARM)
 #define OPENSSL_32_BIT
 #define OPENSSL_ARM
-#elif (defined(__PPC64__) || defined(__powerpc64__)) && defined(_LITTLE_ENDIAN)
-#define OPENSSL_64_BIT
-#define OPENSSL_PPC64LE
 #elif defined(__MIPSEL__) && !defined(__LP64__)
 #define OPENSSL_32_BIT
 #define OPENSSL_MIPS